Scientific Publications
A comprehensive list of peer-reviewed manuscripts detailing our research on the PREP-PP2A axis, related pathologies, and novel therapeutic compounds.
Novel PREP ligand, HUP-46, ameliorates behavioral deficits in an alpha-synuclein based Parkinson's disease model
A prolyl oligopeptidase ligand blocks memory deficit in a repeated mild traumatic brain injury model
5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein–Protein Interaction-Derived Functions
A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy
Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson's Disease
Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A
New tricks of prolyl oligopeptidase inhibitors – A common drug therapy for several neurodegenerative diseases
Protein phosphatase 2A dysfunction in Alzheimer's disease
Prolyl oligopeptidase colocalizes with α-synuclein, β-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinson's and Alzheimer's diseases
Prolyl oligopeptidase: a potential target for the treatment of cognitive disorders